Angiography Pack
| pcs | |
| 150x300 cm Femoral Angiography Drape | 1 |
| 100x150 cm Table Cover | 1 |
| 100x200 cm Drape Sheet | 1 |
| Fluoroscopy Cover | 1 |
| 40 x 40 cm Towel | 2 |
| Solution Bowl 250 cc. | 1 |
| 100x100 cm Wrapping Paper | 1 |
01May
28Apr
Bionano Data Solutions
Bionano Data Solutions
Bionano Data Solutions™ includes a complete suite of hardware and software for end-to-end experiment management, analysis and bioinformatics processing, along with convenient web-based management and monitoring tools.
BIONANO ACCESS
Automate data analysis: monitor and manage Saphyr remotely
Bionano Access™, your web-based hub for Saphyr operations, provides all the software you need for experiment management and Bionano optical genome mapping in one place.
- Set up runs and monitor real-time data quality metrics remotely to flag potential sample quality issues early
- Automatically start de novo assemblies and structural variation analysis when the desired amount of data has been collected
- Visualize and manipulate maps and structural variants
- Analyze trios by filtering through uncommon variants to identify inherited and de novo variants, and export in a dbVar-compliant VCF file
- Find somatic variants by comparing tumor vs matched normal samples
- Find heterogeneous/mosaic variants down to 1% allele fraction
BIONANO COMPUTE ON DEMAND
Reduce infrastructure costs and increase your optical genome mapping capacity
Bionano Compute On Demand is a pay-per-use solution accessible through Bionano Access web server for your Bionano Solve operations. Compute On Demand simplifies the way you perform genome assembly, hybrid scaffolding, and structural variant analysis, without the need for any additional infrastructure, giving you the flexibility and scalability your experiment deserves. Advantages include:
- Analyze large genomes and high number of samples simultaneously
- Perform pipeline analysis operations without worrying about server capacity
- Data encrypted for secure operations
- Data centers compliant with IPAA, CSA, SOC2, ITAR regulations
- Genomic data accessible only to end-users and deleted post-processing
Bionano Compute on Demand requires Bionano Access 1.6.1 which is available on our Software Downloads page.
For more information, download the Bionano Compute On Demand brochure.
TYPICAL NUMBER OF COMPUTE ON DEMAND TOKENS REQUIRED
| Human de Novo Assembly | 1 | Calculated | Max tokens computed based on input molecules. 2 Tbp limit (down sampled to 250x at runtime) |
| Non-Human or No Reference de Novo Assembly | 1 | 50 | Below 300 Gbp |
| Non-Human or No Reference de Novo Assembly | 10 | 150 | 300 - 500 Gbp |
| Non-Human or No Reference de Novo Assembly | 20 | 250 | 500 - 1000 Gbp |
| Non-Human or No Reference de Novo Assembly | 30 | 400 | 1000 - 2000 Gbp |
| Non-Human or No Reference de Novo Assembly | 40 | 500 | 2000 - 3000 Gbp (Limit Increased) |
| Non-Human or No Reference de Novo Assembly | 50 | 650 | 3000 - 4000 Gbp (New Tier) |
| Scaffold | 1 | 30 | |
| Two Enzyme Hybrid Scaffold | 1 | 30 | |
| Variant Annotation (Single) | 1 | 3 | |
| Variant Annotation (dual or trio) | 1 | 10 | |
| Bnx Merge | 1 | 2 | |
| Filter Bnx | 1 | 2 | |
| MQR | 1 | 2 | |
| SV Merge | 1 | 5 | |
| Alignment | 1 | 4 | |
| Rare Variant Analysis | 3 | 25 | 0 - 2000 Gbp |
| Rare Variant Analysis | 5 | 50 | 2000 - 6000 Gbp (New Tier) |
| Bionano Enfocus FSHD Analysis | 1 | 5 | New Operation |
| OPERATION | MIN TOKENS | MAX TOKENS | NOTES |
|---|
*Number of tokens required dependent on the data quality and coverage
SAPHYR COMPUTE SERVER
Enhanced data processing power for high-speed optical genome mapping
The Saphyr Compute Server offers cluster-like performance in an affordable, compact solution. Capable of performing multiple simultaneous analyses and sustaining continuous throughput, the Saphyr Compute Server allows you to spend less time waiting for data so you can focus on investigating results.
- Perform de novo assembly of a human genome in approximately 9 hours
- Simple web-based interface enables integration into virtually any network setup
- Cloud-based solutions available
BIONANO COMPUTE SERVER
Additional power for Saphyr
The Bionano Compute Server is a stand-alone, secondary compute server that offers the ability to perform automated genome assembly, hybrid scaffolding and structural variant calling in parallel with the Saphyr Compute Server. Additional Bionano Compute Servers can be added for increased processing power.
BIONANO DATA SOLUTIONS ORDERING INFORMATION
- Saphyr Compute Server: Part # 80013
- Bionano Compute Server: Part # 80014
- Bionano Compute On Demand, US: Part # 90047
- Bionano Compute On Demand, Germany: Part # 90052
- Bionano Compute On Demand, Europe: Part # 90060
28Apr
Bionano Prep Kits
Bionano Sample Prep Kits: Isolation & Labeling
Bionano Prep Kits™ provide the critical reagents and protocols needed to extract and label high molecular weight (HMW) DNA for use on the Irys® and Saphyr™ systems. Bionano kits are optimized for performing Bionano optical genome mapping applications on a variety of sample types.
HIGH MOLECULAR WEIGHT DNA EXTRACTION
Bionano optical genome mapping begins with the isolation of HMW DNA
Bionano sample kits are optimized for isolating and purifying HMW DNA in a process that is gentler than existing HMW DNA extraction methods. The resulting purified DNA, several megabases in length, is optimal for use with Bionano systems. Each Bionano Prep Kit allows you to perform 5-10 HMW DNA preps. Bionano kits and protocols enable the extraction of HMW DNA from a variety of sample types including soft or fibrous:
- Animal tissue
- Plant tissue
- Cell lines
- Human blood
- Bone Marrow Aspirate (BMA) – NEW!
BIONANO SAMPLE PREP KITS ORDERING INFORMATION
| NEW! 90057 |
Bone Marrow Aspirate(BMA) DNA Isolation kit – 10 reactions | For use with heparin-collected bone marrow aspirates (BMA). Compatible with Bionano DLS DNA Labeling Kit only. First-time users must order Bionano Prep SP Magnetic Retriever (#80031). |
| NEW! 80038 |
SP Tissue and Tumor DNA Isolation kit – 10 reactions | For use with human or animal tissue or tumor. Compatible with Bionano DLS DNA Labeling Kit only. First-time users must order Bionano Prep SP Magnetic Retriever (#80031). |
| 80030 | SP Blood & Cell Culture DNA Isolation Kit – 10 reactions | For use with EDTA-collected blood and mammalian cell cultures. Compatible with Bionano DLS DNA Labeling Kit only. First-time users must order Bionano Prep SP Magnetic Retriever (#80031). |
| 80002 | Animal Tissue DNA Isolation Kit - 10 reactions | For use with soft or fibrous animal tissue. Order with Bionano DLS DNA Labeling Kit or with Bionano NLRS DNA Labeling Kit. |
| 80004 | Blood and Cell Culture DNA Isolation Kit - 10 reactions | For use with blood and cell cultures. Order with Bionano DLS DNA Labeling Kit or with Bionano NLRS DNA Labeling Kit. |
| 80003 | Plant DNA Isolation Kit - 5 reactions | For use with most plant tissues. Order with Bionano DLS DNA Labeling Kit or with Bionano NLRS DNA Labeling Kit. |
| 80005 | DLS DNA Labeling Kit - 10 reactions | Direct Label and Stain Kit for use with Bionano Animal Tissue, Plant, or Blood and Cell Culture DNA Isolation Kits. Not required for using the Bionano Prep Kit. |
| 80001 | NLRS DNA Labeling Kit - 10 reactions | Nicking, Labeling, Repairing and Staining Kit for use with Bionano Animal Tissue, Plant, or Blood and Cell Culture DNA Isolation Kits. Not required for using the Bionano Prep Kit. |
| CATALOG # | COMPONENT | PRODUCT DESCRIPTION |
|---|
LABELING REAGENTS DEVELOPED SPECIFICALLY FOR BIONANO SYSTEMS
Bionano labeling reagents are optimized for applications on Bionano optical genome mapping systems
Starting with HMW DNA purified using the appropriate Bionano prep kit, fluorescent labels are attached to specific sequence motifs. The result is uniquely identifiable genome-specific label patterns that enable de novo map assembly, anchoring sequencing contigs and discovery of structural variations starting at 500 bp.
28Apr
Bionano Chips
Bionano Chips
Built using proprietary Nanochannel technology, Bionano Chips for the Saphyr® and Irys® systems linearize DNA, enabling high-speed, high-throughput optical genome mapping and structural variation detection for a variety of applications including human and clinical research.
SEE DNA AS IT IS MEANT TO BE SEEN
The Bionano Saphyr Chip® and Irys Chip® utilize hundreds of thousands of massively parallel NanoChannels per flow cell that linearize long DNA molecules allowing Bionano systems to directly image your samples.
Inside the chip’s flow cell, a gradient of micro- and nano-structures, upstream of the chip’s NanoChannels, gently unwinds and guides DNA into the NanoChannels. Saphyr Chip’s NanoChannels allow only a single linearized DNA molecule to travel through while preventing the molecule from tangling or folding back on itself.
By leveraging mature semiconductor manufacturing technology, Bionano delivers robust performance and quality. The breakthrough Saphyr Chip combines with the Bionano Direct Label and Staining (DLS) technology to provide you with the highest sensitivity possible for structural variant detection starting at 500 bp, along with genome maps up to chromosome-arm-length.
SPECIFICATIONS AND ORDERING INFORMATION
| Flowcells | 3 | 2 | 2 |
| Total Output (human sample/flowcell) |
5 Tbp* | 1300 Gbp* | 10 Gbp / 50 Gbp |
| Hardware Compatibility | Saphyr Instrument (Part #60325) |
Saphyr Instrument (Part #60239) |
Irys Instrument |
| Catalog Number | 20366 | 20319 | 20249 |
| Specification Sheet | Download Here | Download Here | N/A |
| FEATURES | SAPHYR CHIP G2.3 | SAPHYR CHIP G1.2 | IRYS CHIP |
|---|
Specifications based on Bionano-supplied NA12878 control sample prepared with the Bionano Prep SP kit.
For non-control samples, performance may vary due to a number of factors, including quality of starting material.
*Bionano supplied control sample only
27Apr
Saphyr Optical Genome Mapping Instrument
Saphyr Optical Genome Mapping Instrument
Optical genome mapping using Saphyr® reveals what’s missing in your research. Rapidly identify genome variation like never before with the high-throughput Saphyr system.
STRUCTURAL VARIATION DISCOVERY PLATFORM
Resolve large-scale structural variations missed by next-generation sequencing (NGS) systems
Large structural variations are responsible for many diseases and conditions, including cancers and developmental disorders. Optical genome mapping with Saphyr detects structural variations ranging from 500 bp to megabase pairs in length and offers assembly and discovery algorithms that far outperform sequencing-based technologies in sensitivity.
For mosaic samples or heterogeneous cancer samples, Saphyr detects all types of structural variants down to 1% variant allele fraction. Saphyr provides this performance typically with a false positive rate of less than 2%. Saphyr also calls repeats and complex rearrangements.
Detect large-scale structural variations for genetic disease, cancer, and cytogenomics.
OPTICAL GENOME MAPPING PROVIDES ENHANCED SPEED AND THROUGHPUT
Rapid optical genome mapping using whole-genome imaging for human research applications
Saphyr features enhanced optics with adaptive loading of DNA utilizing machine learning. The Saphyr Instrument and high-capacity Saphyr Chip® combine to deliver genome maps at the speed and scale your research demands.
- Long molecules from 150,000 bp to multi-megabase pairs
- 15 Tbp output per Saphyr Chip for human samples for deep structural variant discovery (5 Tbp per flowcell of molecules larger than 150 kbp)
- Sample to structural variation call or genome scaffolding in as little as 4 days
SIMPLIFIED WORKFLOW
Optical genome mapping automation features and intelligent sample preparation simplify the process
Saphyr optical genome mapping offers automated features that minimize hands-on time.
- Requires less than 3 minutes hands-on instrument time per chip
- Automatic optimization of run conditions based on sample characteristics maximizes throughput
- Saphyr Chip Clip protects sample integrity and eliminates the need for instrument wash cycles between runs
HIGH SPEED DATA COLLECTION
Optical genome mapping automation features and intelligent sample preparation simplify the process
Saphyr runs each genome in its own flow cell. Each Saphyr chip holds three flow cells, and 100x coverage of 3 human genomes is collected in less than 6 hours. That means 12 human samples at 100x coverage per day, or up to 96 per week.
For cases requiring higher coverage, like mosaic samples or heterogeneous tumors, the run can be extended up to 24 hours to collect as much as 400x coverage of a human genome for each of the three flowcells.
AUTOMATED SYSTEM HEALTH MONITORING
Remote quality control ensures maximum performance at all time
The Saphyr Assure Service provides an optional (opt-in required) automated health monitoring feature that continuously inspects data quality and instrument performance. Performance issues are detected before data quality and performance are impacted allowing Bionano Support to proactively repair the system with minimal downtime.
INTELLIGENT DATA SOLUTIONS
Automate data analysis—monitor and manage the Saphyr Instrument remotely
The Bionano suite of hardware and software for Saphyr streamlines your workflow and reduces time to result.
SAMPLE PREPARATION KITS
Extract high-molecular-weight DNA for human, plant and animal genome mapping
The Bionano Prep DLS DNA labeling kit provides all the enzymes, dyes and buffers you need to label non-amplified DNA for Saphyr. Controls for validating the labeling biochemistry are also provided.
SAPHYR ORDERING INFORMATION AND BROCHURE
- Saphyr System with Bionano Access Server: Catalog #90023
- Saphyr Compute Server: Catalog #80013
- Saphyr Chip G2.3* : Catalog #20366
- Saphyr Chip G2.2* : Catalog #20367
- Bionano Compute Server: Catalog #80014
*Compatible only with Saphyr System #90023 (Saphyr Instrument #60325)
22Apr
Telemicroscopy Starter Package
Your immediately available,
affordable and easy-to-implement
telepathology solution.
Bridge distances and keep working from anywhere.
Save time without taking any risk.
Scan and Share Whole Slide Images
1
Step 1
Upgrade your microscope with a camera and the Microvisioneer manualWSI software to a manual scanner.
2
Step 2
Create zoomable Whole Slide Images at the desired magnification.
3
Step 3
Share virtual slides within seconds with anyone via the internet with the Microvisioneer InstaSlide software.
Benefits
Time Saving
Camera and software are immediately available.
Slide sharing is possible wihtin seconds, even with a slow internet connection.
Affordable
No expensive hardware is required.
After 6 months, no further costs occur if the system is not needed anymore.
Easy Implementation and Usage
Easy camera and software installation. Intuitive and user friendly software.
Microvisioneer experts provide support whenever necessary.
Telemicroscopy Starter Package
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6 months starter package
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purchase additional months depending on your needs
Package Content
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For upgrade of microscopes with a trinocular head.
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Microvisioneer manualWSI Scanning Software (does not include fluorescence scanning)
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Microvisioneer InstaSlide Scan Sharing Software
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Camera suitable for manual scanning
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Camera adapter
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Guaranteed shipping within 2-3 business days
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Watch a Quick Demo
22Apr
Instaslide Telemicroscopy
InstaSlide slide sharing software
Share digital slides within seconds with anyone, anywhere.
View slides from any distant location.
Your telemicroscopy solution.
Our software solutions are affordable and immediately available.
Used in 50+ countries worldwide.
InstaSlide
Share digital slides
View digital slides anywhere
Watch a Quick Demo
Slide Sharing with InstaSlide
VIEW THE SHARED ZOOMABLE WHOLE SLIDE IMAGES
Everyone receiving the URL can view the virtual slides now. Nothing more than a web browser is needed.
The scans can be viewed as a zoomable website on any device such as computers, tablets or smartphones.
The capacity of the InstaSlide virtual slides server is unlimited. You can share hundreds of slides within seconds.
Benefits of InstaSlide
Read Slides Anywhere
There is no need to visit remote sites to view slides. Save your precious time and simply ask a colleague to scan slides and share them instantly online via InstaSlide. Slides become accessible with any device at any location.
Show Slides to Anyone
Share difficult slides with your colleagues for a second opinion. They just need a web browser to have a look at the scans.
Save Time
Common upload of scans to to pathology cloud platforms takes a lot of time. InstaSlide shares even terabytes of virtual slides within seconds. Sharing and reading slides via InstaSlide is extremely fast, even with slow internet connections.
Maintain Image Quality
The InstaSlide web viewer does not use the traditional screen sharing technology often used by telemicroscopy solutions. As a result, the image quality is superior to traditional techniques.
Which Scans Can Be Shared?
Generally, all digital images in svs or tiff file format can be shared.
InstaSlide of course works perfectly with Microvisioneer's manual scanning software manualWSI.
As manual slide scanning is much more affordable than motorized scanning, a telemicroscopy workflow can be easily set up anywhere very quickly and without financial risks.
13Jan
Manual Whole Slide Imaging
manualWSI software
Upgrade your microscope to a manual slide scanner.
Start creating virtual microscope slides now for any digital pathology application.
Our software solutions are affordable and immediately available.
Used in 50+ countries worldwide.
Now also available as
Fluorescence-Edition for fluorescence slide scanning!
Manual WSI
by Microvisioneer
Whole Slide Imaging
Watch a Quick Demo
The Manual Scanning Process
UPGRADE YOUR MICROSCOPE TO A MANUAL SCANNER
Convert your existing microscope with a suitable camera and the Microvisioneer manualWSI scanning software to a manual microscope slide scanner.
Camera mounting and software installation is extremely easy and can be done within 5 min.
A simple microscope upgrade - your ticket to virtual microscopy.
CREATE ZOOMABLE WHOLE SLIDE IMAGES...
Digitize your glass slides:
Select any desired objective and scan high-quality zoomable whole slide images or representative subregions of the specimens, using your microscope as whole slide image scanner.
Scanning is intuitive and smooth. Real time image stitching is seamless.
VIEW, ANALYZE, ARCHIVE OR SHARE THE VIRTUAL SLIDES
Microvisioneer virtual slides can be viewed and analyzed by the major available viewers and image analysis tools. Many of them are freely available, such as Sedeen or QuPath. The manual scanner can be integrated into any digital pathology workflow.
For sharing the images, simply use cloud-based systems or find out more about the Microvisioneer InstaSlide virtual slide sharing solution
Zoom into Resulting Whole Slide Images!
Possibilities of Whole Slide Imaging
Image Analysis
Perform representative and reproducible analyses. Automate image analysis.
Documentation
Save your digital slides, annotations and comments.
Education
Scan your own teaching slides and move away from expensive glass slides.
Collaboration
Share virtual microscope slides with your colleagues worldwide. The telepathology solution.
Benefits of Microvisioneer manualWSI
Affordable
No expensive new hardware is required. No maintenance costs occur. The manual scanner can serve as an alternative to an automated scanner or as add-on or back-up.
Time Saving
Immediately available solution. Scanning of smaller areas is often faster compared to automated scanners.
Flexible
Maintains flexibility and features of the microscope.
Versatile
The manual scanning system is suitable for exceptional slides, such as thick or uneven slides.
What Our Customers Say
IT GIVES A CLEAR OVERVIEW. IT IS VERY FAST. IT HAS A GREAT RESOLUTION. IT IS EASY TO FOCUS WHEREEVER YOU NEED IT.
A WORKING SCANNER THAT PRODUCES DIAGNOSTIC QUALITY IMAGES
I CAN USE MY EXISTING EQUIPMENT, NO NEED FOR A MAJOR CAPITAL INVESTMENT. MANY OF THE FEATURES ARE UNIQUE AND USEFUL.
UNPRECEDENTED SMOOTHNESS IN THE IMAGE STITCHING, WHICH IS IMPRESSIVE
PRACTICAL AND EASY USABILITY FOR OIL-BASED SCANNING
Applications
Microvisioneer's manual scanning approach combines digital progress and innovation with the versatility and flexibility of traditional microscopes. With the resulting manual microscope scanner, almost any type of slide can be digitized, no matter how exceptional.
For example, particularly thick slides such as brain tissue sections or uneven slides, which are often a problem for automated scanners, can be perfectly scanned.
Applications range from virtual slides pathology, digital histology, cytology, hematology, veterinary and plant pathology to geology and material science.
Typical brightfield, oil immersion, phase contrast and polarized light imaging are possible as well as fluorescence imaging with the newly available manualWSI-Fluorescence edition.
Explore a few selected applications in more detail in our use case section on this website.
You decide what you scan and at which objective lens magnification.
For research use only.
